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KMID : 1037120220400010052
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The World Journal of Men′s Health
2022 Volume.40 No. 1 p.52 ~ p.65
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Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male
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Agarwal Ashok
Sharma Rakesh
Gupta Sajal
Finelli Renata
Parekh Neel
Selvam Manesh Kumar Panner
Pompeu Camila Pinho
Madani Sarah
Belo Andrea
Darbandi Mahsa
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Abstract
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Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen analysis includes the evaluation of both macroscopic and microscopic parameters, whereas automated semen analysis is conducted through a computer-aided sperm analysis system and can include additional parameters that are not evaluated by manual analysis. Both quality control (QC) and quality assurance (QA) are important to ensure reproducible results for semen analysis, and represent fundamental checks and balances of all stages (pre-analytical, analytical, and post-analytical) of semen analysis. To ensure accuracy and precision, the laboratory technicians' performance should be evaluated biannually. This narrative review aims to describe standardized laboratory procedures for an accurate assessment of semen parameters that incorporate both QC and QA practices.
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KEYWORD
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Semen analysis, Standardization, Quality assurance, Quality control
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